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07/03/2009 05:00 AM
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FDA Adds Strong Warnings To Anti-Smoking Drug Labels
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"The Food and Drug Administration announced (Wednesday) that it is requiring the smoking-cessation drugs Chantix and Zyban to carry the strongest type of safety warning possible to alert patients that the medications can cause serious mental health problems, including depression and suicide," the Washington Post reports (Stein, 7/1).
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07/03/2009 02:00 AM
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In Postpartum Women, Poor Sleep Is Independently Associated With Depression
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A study in the July 1 issue of the journal SLEEP suggests that postpartum depression may aggravate an already impaired sleep quality, as experiencing difficulties with sleep is a symptom of depression.
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07/03/2009 01:00 AM
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What Is Post Traumatic Stress Disorder? What Is PTSD? What Causes PTSD?
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PTSD (Post-Traumatic Stress Disorder) is triggered by a traumatic event - it is a kind of anxiety. The sufferer of PTSD may have experienced or seen an event that caused extreme fear, shock and/or a feeling of helplessness. Most of us experience a brief period of difficulty adjusting and coping with traumatic events. However, we gradually get better with time and healthy coping methods.
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07/02/2009 07:00 AM
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Sepracor Provides Update On Clinical Trials For SEP-225289 And LUNESTA(R) Pediatrics
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Sepracor Inc. (Nasdaq: SEPR) announced that it has completed the analysis and validation of the preliminary results of a Phase II, 514-patient study evaluating the efficacy and safety of SEP-225289 for the treatment of Major Depressive Disorder, including patients with melancholic and atypical features.
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07/02/2009 04:00 AM
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No 'Empty Nest Syndrome' For Parents In Rural Thailand
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So-called 'empty nest syndrome' does not affect parents living in rural areas as much as previously thought, according to a new study carried out in Thailand. In fact, parents whose children have all migrated to urban areas of Thailand are less likely to experience depression than parents whose children stay at home.
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07/02/2009 01:00 AM
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Parkinson's Disease Alters Patient's Ability To Learn From Rewards While Treatment Affects Ability To Learn From Negative Outcomes
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A new neuropsychological memory test is helping to uncover how Parkinson's disease can alter people's ability to learn about the consequences of the choices they make. The test was developed by Dr. Mark Gluck, professor of neuroscience at the Center for Molecular and Behavioral Neuroscience at Rutgers University, Newark, working with co-researchers at Rutgers, New York University, and in Hungary.
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06/29/2009 04:00 AM
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Study Links Depressive Mood, Racial Disparities In Preterm Birth
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Women who have depression symptoms prior to becoming pregnant are at an increased risk for having preterm births, with the risk twice as high for black women as for white women, according to a study in the Journal of Women's Health, Reuters reports.
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06/28/2009 01:00 AM
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Antidepressant Directly Stimulates Brain Growth Factor Receptors
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The widely used antidepressant and pain medication amitriptyline--but not other closely related drugs -- can impersonate the brain's own growth factors, researchers at Emory University School of Medicine have shown. The results are published online and will appear in the June 26 issue of the journal Chemistry & Biology.
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06/26/2009 01:00 AM
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Irritability Should Be Considered When Diagnosing Bipolar Disorder In Children
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A new study from Bradley Hospital and The Warren Alpert Medical School of Brown University, as well as two other institutions, adds to mounting evidence that clinicians consider irritability as a symptom when diagnosing pediatric bipolar disorder.
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06/24/2009 05:00 AM
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Care Management Reduces Depression And Suicidal Thoughts In Older Primary Care Patients
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Depression in older adults too often goes unrecognized and untreated, resulting in untold misery, worsening of medical illness, and early death. A new study has identified one important remedy: Adding a trained depression care manager to primary care practices can increase the number of patients receiving treatment, lead to a higher remission rate of depression, and reduce suicidal thoughts.
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06/24/2009 05:00 AM
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Gene Theory For Depression Is Now Discredited
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A study that attempted to replicate the "seminal" study that laid the foundation for psychiatry's "serotonin theory" of depression, claiming a genetic- serotonin impairment underlying depression, has been debunked by the data from 14 similar studies claiming a genetic underpinning to depression.
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06/24/2009 03:00 AM
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Psychotherapy Of Depression Changes Biological Parameters?
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A group of German investigators demonstrated that the early increase in phosphorylated CREB (pCREB) is related to treatment response and does not depend on pharmacological interventions or brain-derived neurotrophic factor (BDNF) plasma levels. For the first time, cellular biological markers could be associated with response to psychotherapy.
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06/24/2009 03:00 AM
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What Is The Risk Of Obesity While Taking Antidepressant Drugs?
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Cross-sectional studies have reported an association between major depressive episode (MDE) and obesity. The objective of this longitudinal analysis was to determine whether MDE increase the risk of becoming obese over a 10-year period. Data from the Canadian National Population Health Survey (NPHS) were used, a longitudinal study of a representative cohort of household residents in Canada.
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06/22/2009 04:00 AM
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Clinical Data, Inc. Announces Approval Of Generic Name Vilazodone, First In A New Class Of Experimental Treatments For Depression
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Clinical Data, Inc. (NASDAQ: CLDA) announced today that the United States Adopted Name Council (USAN) has approved the generic name vilazodone hydrochloride.
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06/18/2009 11:00 AM
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What Is Mental Health? What Is Mental Disorder?
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Mental health refers to our cognitive, and/or emotional wellbeing - it is all about how we think, feel and behave. Mental health, if somebody has it, can also mean an absence of a mental disorder. Approximately 25% of people in the UK have a mental health problem during their lives. The USA is said to have the highest incidence of people diagnosed with mental health problems in the developed world.
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06/18/2009 09:00 AM
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Stanford Medical Center Announces $100,000 Planning Grant For Community Response To Teen Depression And Suicide
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Enhancing the response to teen depression and suicide is the focus of a new planning grant announced on June 12 by the Stanford Medical Center. The $100,000 grant, funded by Lucile Packard Children's Hospital, the Stanford University School of Medicine and Stanford Hospital & Clinics, will support collaboration among Palo Alto-area providers of health care resources for teens.
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06/18/2009 05:00 AM
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How Much Chronic Depression With Medical Disorders Affect Work Performance?
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A group of Australian researchers investigated in medical disorders the effects of comorbid dysthymic disorder as compared to major depressive disorder (MDD) on health-related quality of life (HR-QoL) and disability days in the general population. In a population-based study 4,181 individuals were assessed for the presence of dysthymic disorder and depression, utilizing the Composite International Diagnostic Interview.
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06/18/2009 02:00 AM
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Analysis Does Not Support Association Between Genetic Marker, Stress And Risk Of Depression
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Contrary to a previous report, an analysis of 14 previous studies does not find an association between a serotonin transporter gene variation, stressful life events, and an increased risk of major depression, according to an article in the June 17 issue of JAMA. The authors did find that the number of stressful life events is associated with depression.
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06/17/2009 05:00 AM
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Study Pinpoints Links Of Depression With Chronic Pain
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It is well known that chronic pain and clinical depression go together, but a study in The Journal of Pain, published by the American Pain Society, shows that the connection between pain and depression is strongest in middle-age women and African Americans. Researchers at Wayne State University studied a representative community sample of 1,100 Michigan residents and found that the incidence of chronic pain, defined as pain persisting for six months, was 22 percent.
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06/17/2009 01:00 AM
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New Animal Study Of Rexahn's Serdaxinâ„¢ Shows Drug's Promise To Treat Anxiety And Depression With Minimal Side Effects
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Rexahn Pharmaceuticals, Inc. (NYSE Amex: RNN), announced the results of a wide-ranging animal study offering more evidence that Serdaxinâ„¢ may be an effective therapeutic for the treatment of anxiety disorders in humans. Serdaxin is Rexahn's leading anxiety and depression drug candidate, and is currently in Phase II clinical trials.
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06/16/2009 04:00 AM
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Depression May Increase Risk Of Alzheimer's Disease In People With Memory Problems
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People with memory problems who are depressed are more likely to develop Alzheimer's disease compared to people who are not depressed, according to a study published in the June 16, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology. However, the research also shows that the popular Alzheimer's drug donepezil may delay the progression to Alzheimer's disease for depressed people with mild cognitive impairment (MCI) or memory problems.
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06/16/2009 04:00 AM
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Update On Lu AA21004 Clinical Development Programme In Major Depressive Disorder (MDD)
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H. Lundbeck A/S (Lundbeck) and Takeda Pharmaceutical Company Limited (Takeda) jointly announced headline results from the first three clinical trials in the phase III development programme with Lu AA21004 in major depressive disorder (MDD). Previously reported clinical phase II data showed equal efficacy with the 5 and 10 mg doses. In the recently completed phase III clinical trials, Lu AA21004 was tested in doses of 2.5, 5 and 10 mg.
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06/16/2009 03:00 AM
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63 Percent Of RA Patients Suffer Psychiatric Disorders, With Depressive Spectrum Conditions Most Likely
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Over half (63%) of patients with rheumatoid arthritis (RA) also suffer from psychiatric disorders, with the majority of these (87%) occurring in the depressive spectrum, according to the results of a new study presented recently at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. Interestingly, over half (52%) of the patients studied indicated that they had experienced stress events before the onset of their RA.
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06/16/2009 03:00 AM
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Depression May Increase Risk Of Alzheimer's
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US researchers found that people with memory problems who are depressed are at higher risk of developing Alzheimer's disease than people who are not depressed, and that the popular Alzheimer's drug donepezil (brand name Aricept) may delay progress to Alzheimer's in depressed people who have memory problems or mild cognitive impairment (MCI).
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06/16/2009 02:00 AM
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Anxiety And Depression Lower Quality Of Life In Majority Of Systemic Lupus Erythematosus Patients
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92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which significantly affects both their physical and emotional quality of life (QoL), according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. Logistic regression analysis revealed that depression was the most significant factor shown to affect QoL (p=0.015; OR=0.18; CI 95%:0.045-0.72).
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